3-甲基己二酸是植烷酸分解代谢的代谢产物。患有成人雷夫苏姆斯病 (ARD) 的患者无法通过 α-氧化来解毒植烷酸，因此 w-氧化途径是植烷酸降解的唯一代谢途径。

Transglutaminase (EC 2.3.2.13) 是一种在蛋白质分子之间形成交联的酶。Transglutaminase 催化谷氨酰胺残基的 γ-羧酰胺基团与不同化合物的一级 ε-胺基团之间形成异肽键。Transglutaminase 参与许多生理过程，包括凝血、抗菌免疫反应和光合作用。

E-3030 free acid is a peroxisome proliferator-activated receptor (PPAR) agonist. E-3030 decreased blood glucose, triglyceride, non-esterified fatty acids, and insulin levels and increased blood adiponectin levels. Triglyceride- and non-high-density lipoprotein cholesterol-lowering actions of E-3030 involve combined effects on reduction of apo C-III and elevation of lipoprotein lipase, resulting in increased lipolysis.