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β-Aminoarteether
CAS No. 133162-24-0
β-Aminoarteether ( —— )
产品货号. M35062 CAS No. 133162-24-0
β-Aminoarteether (SM934 free base) 是一种具有口服活性的 Artemisinin 衍生物。β-Aminoarteether 可用于炎症和自身免疫性疾病的研究，例如狼疮疾病。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥2841 | 有现货 |
|
| 10MG | ￥4171 | 有现货 |
|
| 25MG | ￥6426 | 有现货 |
|
| 50MG | ￥8816 | 有现货 |
|
| 100MG | ￥11520 | 有现货 |
|
| 500MG | ￥23040 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
| 1 mL x 10 mM in DMSO | ￥2679 | 有现货 |
|
生物学信息
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产品名称β-Aminoarteether
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述β-Aminoarteether (SM934 free base) 是一种具有口服活性的 Artemisinin 衍生物。β-Aminoarteether 可用于炎症和自身免疫性疾病的研究，例如狼疮疾病。
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产品描述β-Aminoarteether (SM934 free base) is an Artemisinin derivative with orally active. β-Aminoarteether can be used for inflammation and autoimmune disease research, such as lupus diseases.
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体外实验β-Aminoarteether (SM934;10 μM; 24 hours) treatment directly enhances IL-10 production and suppresses IL-12/23p40 production in primary peritoneal macrophages with IFN-γ stimulation. In vitro, β-Aminoarteether (SM934) could suppress the Th1 and Th17 polarization, but exerted no influence on Treg differentiation.
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体内实验β-Aminoarteether (SM934; 1-10 mg/kg; oral administration; daliy; for 3 months) treatment significantly delays the progression of glomerulonephritis and increases the survival rate of NZB/W F1 mice. β-Aminoarteether treatment promots the IL-10 production of macrophages from NZB/W F1 mice.Animal Model:Female NZB/W F1 mice (Six and half months old) Dosage:1 mg/kg, 3 mg/kg, and 10 mg/kg Administration:Oral administration; daliy; for 3 months Result:Significantly delayed the progression of glomerulonephritis and increased the survival rate of NZB/W F1 mice.
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同义词——
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通路Others
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靶点Other Targets
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受体Others
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研究领域——
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适应症——
化学信息
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CAS Number133162-24-0
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分子量327.42
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分子式C17H29NO5
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纯度>98% (HPLC)
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溶解度——
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SMILESC[C@@H]1[C@]2([C@]34[C@@](O[C@](C)(OO3)CC[C@]4([C@H](C)CC2)[H])(O[C@@H]1OCCN)[H])[H]
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Li-Fei Hou, et al. SM934 treated lupus-prone NZB × NZW F1 mice by enhancing macrophage interleukin-10 production and suppressing pathogenic T cell development. PLoS One. 2012;7(2):e32424.?
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