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Ac-LETD-AFC

CAS No. 210345-02-1

Ac-LETD-AFC ( —— )

产品货号. M34831 CAS No. 210345-02-1

Ac-LETD-AFC 是一种 caspase-8 荧光底物。Ac-LETD-AFC 可检测 caspase-8 荧光活性,用于肿瘤细胞凋亡和氧化应激代谢的研究。

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥941 有现货
10MG ¥1663 有现货
25MG ¥2688 有现货
50MG ¥3841 有现货
100MG ¥5031 有现货
200MG ¥6768 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    Ac-LETD-AFC
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    Ac-LETD-AFC 是一种 caspase-8 荧光底物。Ac-LETD-AFC 可检测 caspase-8 荧光活性,用于肿瘤细胞凋亡和氧化应激代谢的研究。
  • 产品描述
    Ac-LETD-AFC is a caspase-8 fluorogenic substrate. Ac-LETD-AFC can measure caspase-8 fluorogenic activity and can be used for the research of cancer cell apoptosis and oxidative stress metabolism.
  • 体外实验
    Guidelines (Following is our recommended protocol. This protocol only provides a guideline, and should be modified according to your specific needs).Caspase activity assay:1. Incubate the cells according to your normal protocol.2. Wash cells once with PBS and centrifugate.3. Resuspend cells in PBS at a concentration of 1× 107 cells/mL.4. Prepare the standard reaction buffer which includ 100 μM caspase-8 substrate AC-LETD-AFC. Prepare correspounding standard reaction buffer according to your protocol.5. Add 15 ul of the cells suspension to a microplate, and mixed with the appropriate peptide substrate dissolved in a standard reaction buffer.
  • 体内实验
    ——
  • 同义词
    ——
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    Others
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    210345-02-1
  • 分子量
    729.65
  • 分子式
    C31H38F3N5O12
  • 纯度
    >98% (HPLC)
  • 溶解度
    ——
  • SMILES
    C(F)(F)(F)C=1C=2C(=CC(NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC(C)C)NC(C)=O)=O)CCC(O)=O)=O)[C@@H](C)O)=O)CC(O)=O)=O)=CC2)OC(=O)C1
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1. Ignacio Bejarano, et al. Melatonin enhances hydrogen peroxide-induced apoptosis in human promyelocytic leukaemia HL-60 cells. Mol Cell Biochem. 2011 Jul;353(1-2):167-76.?
产品手册
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