5-Amino-5-deoxyadenosine ( —— )

产品货号. M33704 CAS No. 14365-44-7

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

5-Amino-5-deoxyadenosine
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

5'-Amino-5'-deoxyadenosine (NH2dAdo; Nsc 238990) 是一种嘌呤核苷类似物。嘌呤核苷类似物具有广泛的抗肿瘤活性，靶向惰性淋巴系统恶性肿瘤。这一过程中的抗癌机制依赖于抑制 DNA 合成，诱导细胞凋亡 (apoptosis) 等。
产品描述

5'-Amino-5'-deoxyadenosine (NH2dAdo; Nsc 238990) is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
体外实验

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体内实验

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同义词

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通路

Apoptosis
靶点

Apoptosis
受体

Apoptosis | Adenosine Receptor
研究领域

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适应症

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1. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.?

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