Tiopinac

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Tiopinac (RS 40974) 是一种二苯并噻吩，是具有口服活性且高度有效的抗炎和解热剂。

Tiopinac (RS 40974), a dibenzthiepin, is an orally active and highly potent anti-inflammatory and anti-pyretic agent.

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Tiopinac (0.03-110 mg/kg) has 40 times the antiphlogistic potency of phenylbutazone. The dose required to reduce paw swelling by 30% is approximately 0.5 mg/kg. Tiopinac does not elicit overt side effects at the 20 mg/kg/day dose. Tiopinac causes a dose-related reversal of the decreases body weight caused by the adjuvant disease, the weight of those rats receiving 0.135 and 0.4 mg/kg/day being significantly greater than that of the positive controls. Tiopinac (0.3-30 mg/kg) is highly potent in inhibiting the pain evoked in the yeastinflamed hind paw of the rat.

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GPCR/G Protein

Prostaglandin Receptor

Prostaglandin Receptor

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61220-69-7

284.33

C16H12O3S

>98% (HPLC)

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OC(=O)Cc1ccc2c(SCc3ccccc3C2=O)c1

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(-20℃)

With Ice Pack

≥ 2 years