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Ropidoxuridine
CAS No. 93265-81-7
Ropidoxuridine ( —— )
产品货号. M33483 CAS No. 93265-81-7
Ropidoxuridine (IPdR) 是一种新型口服，卤化胸苷类似物，有希望用于人类肿瘤的增敏剂。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥979 | 有现货 |
|
| 10MG | ￥1577 | 有现货 |
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| 25MG | ￥2483 | 有现货 |
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| 50MG | ￥3404 | 有现货 |
|
| 100MG | ￥4419 | 有现货 |
|
| 200MG | ￥5958 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
| 1 mL x 10 mM in DMSO | ￥1074 | 有现货 |
|
生物学信息
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产品名称Ropidoxuridine
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述Ropidoxuridine (IPdR) 是一种新型口服，卤化胸苷类似物，有希望用于人类肿瘤的增敏剂。
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产品描述Ropidoxuridine (IPdR) is a novel orally available, halogenated thymidine analog and is a potential radiosensitizer for use in human tumors.
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体外实验Ropidoxuridine is an orally bioavailable pro-drug of IUdR (5-iodo-2'-deoxyuridine). Ropidoxuridine demonstrates strong synergy effects with Alisertib at clinically relevant concentrations.
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体内实验In an orthotopic tumor model, Ropidoxuridine (750 mg/kg/day) and Alisertib (30 mg/kg/day) demonstrate strong synergy effects.
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同义词——
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通路Others
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靶点Other Targets
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受体Others
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研究领域——
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适应症——
化学信息
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CAS Number93265-81-7
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分子量338.1
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分子式C9H11IN2O4
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纯度>98% (HPLC)
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溶解度In Vitro:?DMSO 中的溶解度 : 250 mg/mL (739.43 mM; 超声助溶 )
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SMILESOC[C@H]1O[C@H](C[C@@H]1O)n1cc(I)cnc1=O
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Rampurwala MM, et al. Ropidoxuridine (IPdR) potentiates alisertib (MLN8237) activity in triple-negative breast cancer. [abstract]. In: Proceedings of the Thirty-Eighth Annual CTRC-AACR San Antonio Breast Cancer Symposium: 2015 Dec 8-12; San Antonio, TX. Philadelphia (PA): AACR; Cancer Res 2016;76(4 Suppl):Abstract nr P6-13-16.
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