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Fluzinamide
CAS No. 76263-13-3
Fluzinamide ( —— )
产品货号. M33360 CAS No. 76263-13-3
Fluzinamide 是一种有效的抗癫痫剂。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥11970 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Fluzinamide
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述Fluzinamide 是一种有效的抗癫痫剂。
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产品描述Fluzinamide is an effective antiepileptic.
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体外实验——
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体内实验Fluzinamide, an antiepileptic agent effective against partial seizures, is metabolized extensively in mice, rats and dogs.The anticonvulsant properties of Fluzinamide (AHR-8559) are evaluated in the kindled amygdaloid seizure model in rats. Fluzinamide significantly attenuates afterdischarge durations and the severity of the accompanying convulsive responses in previously kindled rats at doses that does not cause sedation or ataxia. After acute intraperitoneal injections, the maximum anticonvulsant effectiveness against suprathreshold (400 μA) stimulation is seen at 30 min. Fluzinamide (10-80 mg/kg i.p.) is also evaluated in kindled rats using threshold (20 μA increments) seizures. Low doses of Fluzinamide significantly elevate seizure threshold and reduce both elicited after discharge durations and seizure severity. When administered daily during kindling acquisition, Fluzinamide (20 and 40 mg/kg i.p.) significantly increases the number of trials necessary to complete kindling. The duration and the severity of the responses induced by stimulations during the acquisition period are reduced.
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同义词——
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通路Others
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靶点Other Targets
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受体Others
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研究领域——
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适应症——
化学信息
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CAS Number76263-13-3
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分子量274.24
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分子式C12H13F3N2O2
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纯度>98% (HPLC)
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溶解度——
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SMILESO(C1CN(C(NC)=O)C1)C2=CC(C(F)(F)F)=CC=C2
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Johnson DN, et al. Pharmacodynamics and pharmacokinetics of AHR-11748, a new antiepileptic agent, in rodents. Epilepsy Res. 1990 Apr;5(3):185-91.?
