Diazo Biotin-PEG3-alkyne
CAS No. 1884349-58-9
Diazo Biotin-PEG3-alkyne ( —— )
产品货号. M33339 CAS No. 1884349-58-9
Diazo Biotin-PEG3-alkyne 是一种 PROTAC linker,属于 PEG 类。可用于合成 PROTAC 分子。Diazo Biotin-PEG3-alkyne 是一种点击化学试剂。它含有 Alkyne 基团,可以和含有 Azide 基团的分子发生铜催化的叠氮-炔环加成反应 (CuAAc)。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ¥1416 | 有现货 |
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| 10MG | ¥2119 | 有现货 |
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| 25MG | ¥3515 | 有现货 |
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| 50MG | ¥5933 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Diazo Biotin-PEG3-alkyne
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述Diazo Biotin-PEG3-alkyne 是一种 PROTAC linker,属于 PEG 类。可用于合成 PROTAC 分子。Diazo Biotin-PEG3-alkyne 是一种点击化学试剂。它含有 Alkyne 基团,可以和含有 Azide 基团的分子发生铜催化的叠氮-炔环加成反应 (CuAAc)。
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产品描述Diazo Biotin-PEG3-alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. Diazo Biotin-PEG3-alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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体外实验PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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体内实验——
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同义词——
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通路Others
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靶点Other Targets
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受体PROTACs
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研究领域——
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适应症——
化学信息
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CAS Number1884349-58-9
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分子量795.95
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分子式C39H53N7O9S
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纯度>98% (HPLC)
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溶解度——
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SMILESC(CCCC(NCCOCCOCCOCCNC(=O)C1=CC=C(N=NC2=CC(CCNC(CCOCC#C)=O)=CC=C2O)C=C1)=O)[C@H]3[C@@]4([C@](CS3)(NC(=O)N4)[H])[H]
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
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(His32,Leu34)-Neurop...
(His32,Leu34)-Neuropeptide Y (32-36)
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NCGC00135472
NCGC00135472 (DRV1 (GPR32) agonist C2A) is a human Resolvin DI receptor DRV1 agonist with pro-catabolic properties that activates the human soluble protein D1 receptor DRV1/GPR32 receptor in beta-blocker and cAMP assays with EC50s of 0.37 uM and 0.05 uM, respectively.NCGC00135472 induces in cells overexpressing recombinant DRV1 rapid impedance changes that stimulate phagocytosis of serum-treated zymoglycans.
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ACTH 1-13
ACTH (1-13) is a 13-aa peptide, with cytoprotective effects in the model of ethanol induced gastric lesions in rats.Adrenocorticotropic hormone (ACTH), also known as corticotropin, is produced and secreted by the anterior pituitary gland. ACTH is an important component of the hypothalamic-pituitary-adrenal axis as a response to biological stress.
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