Bermoprofen

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Bermoprofen (AD-1590) 是一种具有口服活性地非甾体类抗炎药。Bermoprofen 具有有效的解热作用，且生物半衰期短。Bermoprofen 是 LPS 诱导的兔发烧的有效拮抗剂。

Bermoprofen (AD-1590) is an orally active non-steroidal anti-inflammatory agent. Bermoprofen has potent antipyretic activities with a short biological half-life. Bermoprofen is a potent antagonist of LPS-induced fever in rabbits.

Bermoprofen (AD-1590) shows ulcerogenic activity as a side-effect like other nonsteroidal anti-inflammatory agents.

Bermoprofen (AD-1590) (0.04-0.1 mg/kg; p.o.) shows a dose-related antipyretic activity in LPS-induced febrile rabbits.Animal Model:Male albino rabbits, 2.3-3 kg Dosage:0.04, 0.4, 0.1 mg/kg Administration:Oral; given 1 h after i.v. injection of LPS Result:Inhibited significantly the rise in rectal temperature at doses of 0.1 mg/kg or more, the temperature returned approximately to normal after 0.4 mg/kg.

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Others

Other Targets

Others

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78499-27-1

296.32

C18H16O4

>98% (HPLC)

In Vitro:?DMSO 中的溶解度 : 100 mg/mL (337.47 mM; 超声助溶 )

O=C(O)C(C1=CC=C2OC3=CC=C(C=C3CC(=O)C2=C1)C)C

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(-20℃)

With Ice Pack

≥ 2 years