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(Rac)-WAY-161503
CAS No. 75704-24-4
(Rac)-WAY-161503 ( —— )
产品货号. M33171 CAS No. 75704-24-4
(Rac)-WAY-161503 是一种有效的，选择性的，高亲和力的 5-HT2C 受体激动剂，Ki 为 4 nM，EC50 为 12 nM。(Rac)-WAY-161503 对 HT2C 的亲和力分别比 5-HT2A 和 5-HT2B 受体高。(Rac)-WAY-161503 具有抗肥胖和抗抑郁的作用。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥567 | 有现货 |
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| 10MG | ￥791 | 有现货 |
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| 25MG | ￥1250 | 有现货 |
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| 50MG | ￥1823 | 有现货 |
|
| 100MG | ￥2583 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称(Rac)-WAY-161503
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述(Rac)-WAY-161503 是一种有效的，选择性的，高亲和力的 5-HT2C 受体激动剂，Ki 为 4 nM，EC50 为 12 nM。(Rac)-WAY-161503 对 HT2C 的亲和力分别比 5-HT2A 和 5-HT2B 受体高。(Rac)-WAY-161503 具有抗肥胖和抗抑郁的作用。
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产品描述(Rac)-WAY-161503 is a potent, selective, highly affinity 5-HT2C receptor agonist with a Ki of 4 nM and an EC50 of 12 nM. (Rac)-WAY-161503 displays higher affinity for 5-HT2C than 5-HT2A and 5-HT2B receptors. (Rac)-WAY-161503 has anti-obesity and antidepressant effects.
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体外实验——
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体内实验Animal Model:Male C57BL/6J mice with hallucinogen 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI) Dosage:3 mg/kg, 10 mg/kg, 30 mg/kg Administration:Intraperitoneal injection (i.p.)Result:Dose-dependently decreased locomotor activity, an effect that was blocked by the 5-HT2C/2B antagonist SER-082.
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同义词——
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通路GPCR/G Protein
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靶点5-HT Receptor
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受体5-HT Receptor
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研究领域——
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适应症——
化学信息
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CAS Number75704-24-4
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分子量272.13
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分子式C11H11Cl2N3O
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纯度>98% (HPLC)
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溶解度In Vitro:?DMSO 中的溶解度 : 100 mg/mL (367.47 mM; 超声助溶 )
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SMILESClc1cc2NC(=O)C3CNCCN3c2cc1Cl
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Halberstadt AL, et al. 5-HT(2A) and 5-HT(2C) receptors exert opposing effects on locomotor activity in mice. Neuropsychopharmacology. 2009 Jul;34(8):1958-67.?
产品手册
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