AVE5688 ( —— )

产品货号. M32794 CAS No. 613260-13-2

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

产品询价大包装询价加入购物车

产品名称

AVE5688
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

AVE5688 是糖原磷酸化酶 (glycogen phosphorylase (GP)) 抑制剂，抑制兔肌肉糖原磷酸化酶 rmGPb 和 rmGPa 的活性，IC50 值分别为 430 nM 和 915 nM，Kd 值分别为 170 nM 和 530 nM；AVE5688 可用于二型糖尿病的研究。
产品描述

AVE5688 is an inhibitor of glycogen phosphorylase (GP), with IC50s of 430 nM and 915 nM and Kds of 170 nM and 530 nM for rabbit muscle glycogen phosphorylase (rmGPb and rmGPa, respectively); AVE5688 can be used for the research of type 2 diabetes.
体外实验

AVE5688 is an inhibitor of glycogen phosphorylase (GP), with IC50s of 430 nM and 915 nM and Kds of 170 nM and 530 nM for rabbit muscle glycogen phosphorylase (rmGPb and rmGPa, respectively).
体内实验

——
同义词

——
通路

Others
靶点

Other Targets
受体

Phosphorylase
研究领域

——
适应症

——

1. Anderka O, et al. Thermodynamic characterization of allosteric glycogen phosphorylase inhibitors. Biochemistry. 2008 Apr 22;47(16):4683-91.?

计算器

产品手册

关联产品

Kaempferol 3,7-di-O-...

Kaempferol-3,7-di-O-β-glucoside (Kaempferol 3,7-diglucoside) is a flavonol from Morettia philaena, It can inhibit α-amylase, α-glucosidase and Acetylcholinesterase. Kaempferol-3, 7-di-o-β-Glucoside has neuroprotective activity and can slow down differentiated neuronal cells SH-SY5Y from Amyloid β peptide-induced damage.
PGLa TFA (102068-15-...

PGLa TFA is a cationic antimicrobial peptide (AMP) originally isolated from frog. It has been shown to have antibacterial,antifungal,and antiviral,activities.
Baccatin III

浆果赤霉素 III 是太平洋红豆杉 (Taxus brevifolia) 及相关物种的分离株。浆果赤霉素 III 是抗 Y 药物紫杉醇 (Taxol) 的前体。