Selective, high affinity, non-competitive α1A adrenoceptor antagonist (Ki = 0.35 nM). Exhibits no significant activity against a range of other GPCRs, including α2A, β1 and β2 adrenoceptors. Antagonizes effects of phenylephrine on isolated rabbit prostate muscle in vitro and on intra-urethral pressure in rats.

Thalidomide-O-amido-PEG2-C2-NH2 TFA 是一种合成的 E3 连接酶配体-接头缀合物，其中包含 PROTAC 技术中使用的基于 Thalidomide 的 cereblon 配体和 2 单元 PEG 连接体。

Chlorotoxin TFA is a polypeptide derived from scorpion poison and ACTS as a chloride channel blocker.