KISS1-305

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

KISS1-305, the Metastin/Kisspeptin analog, is a prototype peptide and a chemical probe. KISS1-305 has suboptimal KISS1R agonistic activity, and resists plasma protease degradation.KISS1-305 is a proto- type peptide that resists plasma protease degradation but has suboptimal KISS1R agonistic activity in vitro.

KISS1-305, the Metastin/Kisspeptin analog, is a prototype peptide and a chemical probe. KISS1-305 has suboptimal KISS1R agonistic activity, and resists plasma protease degradation.KISS1-305 is a proto- type peptide that resists plasma protease degradation but has suboptimal KISS1R agonistic activity in vitro.(In Vivo):KISS1-305 (4 nmol/h; s.c.) shows suppression of pituitary-gonadal functions. KISS1-305 causes substantial elevations of plasma LH and testosterone, followed by abrupt reductions of both hormone levels.?KISS1-305 also reduced genital organ weight more profoundly than leuprolide. In mechanistic studies, chronic KISS1-305 administration only transiently induced c-Fos expression in GnRH neurons, suggesting that GnRH-neural response was attenuated over time.

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Others

Other Targets

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872717-97-0

1165.3

C56H76N16O12

>98% (HPLC)

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(-20℃)

With Ice Pack

≥ 2 years