L-JNKI-1
CAS No. ——
L-JNKI-1 ( —— )
产品货号. M30052 CAS No. ——
L-JNKI-1 is a cell-permeable peptide inhibitor specific for JNK, it has been shown to effectively inhibit JNK activity in in vivo studies.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 100MG | 获取报价 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
-
产品名称L-JNKI-1
-
注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
-
产品简述L-JNKI-1 is a cell-permeable peptide inhibitor specific for JNK, it has been shown to effectively inhibit JNK activity in in vivo studies.
-
产品描述L-JNKI-1 is a cell-permeable peptide inhibitor specific for JNK, it has been shown to effectively inhibit JNK activity in in vivo studies. (In Vivo):L-JNKI-1 has been shown to effectively inhibit JNK activity in in vivo studies. It is shown that Ang II induces a dose-dependent pressor response, which was significantly attenuated by JNK inhibition. It is also found that 10 μM L-JNKI-1 decreases phosphorylated c-Jun by 98% and phosphorylated Elk-1 by 100%. L-JNKI-1 is able to across the blood-brain barrier and penetrate neurons of adult mice and P5 rats within 1 h after an intraperitoneal injection.
-
体外实验——
-
体内实验——
-
同义词——
-
通路Others
-
靶点Other Targets
-
受体JNK
-
研究领域——
-
适应症——
化学信息
-
CAS Number——
-
分子量3822.44
-
分子式C164H286N66O40
-
纯度>98% (HPLC)
-
溶解度H2O : ≥ 100 mg/mL (26.16 mM)
-
SMILES——
-
化学全称Sequence:Asp-Gln-Ser-Arg-Pro-Val-Gln-Pro-Phe-Leu-Asn-Leu-Thr-Thr-Pro-Arg-Lys-Pro-Arg-Pro-Pro-Arg-Arg-Arg-Gln-Arg-Arg-Lys-Lys-Arg-Gly-NH2
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
Zhou MS, et al. Role of c-Jun N-terminal kinase in the regulation of vascular tone. J Cardiovasc Pharmacol Ther. 2010 Mar;15(1):78-83.
产品手册
关联产品
-
15-Lipoxygenase Inhi...
15-Lipoxygenase Inhibitor 1 是 15-lipoxygenase 的选择性抑制剂。
-
Humanin (human)
Humanin 是一种 24 个氨基酸组成的抗凋亡肽,是 Bax 抑制剂。Humanin 可以阻止 Bax 从细胞质向线粒体的转运,阻断 Bax 由活性构象向活性构象的转变。Humanin 是一种线粒体相关肽,具有对抗 AD 相关神经毒性的神经保护作用。Humanin 还可以改善动物的整体胰岛素敏感性。Humanin 与衰老有关。HNG,是 Humanin 的 14号位置的丝氨酸被甘氨酸取代的类似物。
-
AK-778-XXMU
AK-778-XXMU是DNA结合2 (ID2) 拮抗剂的有效抑制剂,KD为129 nM。AK-778-XXMU 能抑制胶质瘤细胞株的迁移和侵袭,诱导细胞凋亡 (apoptosis),更重要的是能减缓肿瘤生长。
021-51111890
购物车()
sales@molnova.cn

