Coryneine ( Trimethyl(3,4-dihydroxyphenethyl)aminium | Dopamine methiodide | )

产品货号. M29453 CAS No. 7224-66-0

COA

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产品名称

Coryneine
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Coryneine 是从附子根中提取的多巴胺的季铵衍生物。
产品描述

Coryneine is a quaternary ammonium derivative of dopamine derived from aconite root.(In Vivo):Coryneine (20-150 microM) blocked the nerve-evoked twitch response without affecting the contraction evoked by electrical stimulation of the muscle. Coryneine (20 microM-2mM) itself depolarized the endplate membrane and this effect was reversibly suppressed by 1 and 5 microM pancuronium. Coryneine 30 microM-10mM) produced contractions of denervated muscles in a concentration-dependent manner and the effects were reduced by 70nM pancuronium.
体外实验

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体内实验

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同义词

Trimethyl(3,4-dihydroxyphenethyl)aminium | Dopamine methiodide |
通路

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靶点

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