Yangambin

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Yangambin 是血小板活化因子 (PAF) 心血管作用的选择性拮抗剂；它具有降血压作用，这可能是由于外周血管舒张，至少涉及通过电压门控 Ca2+ 通道抑制 Ca2+ 流入。 Yangambin具有中枢神经系统活性，在野外、强迫游泳和戊巴比妥睡眠时间测试中呈现抑制活性。

Yangambin is a selective antagonist of the cardiovascular effects of platelet activating factor (PAF); it has hypotensive effect, which is probably due to a peripheral vasodilatation that involves, at least, the inhibition the Ca2+ influx through voltage-gated Ca2+ channels. Yangambin has central nervous system activity, it presents a depressant activity in the open field, forced swimming and pentobarbital sleeping time tests.

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GPCR/G Protein

Calcium Channel

Calcium Channel

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13060-14-5

446.496

C24H30O8

>98% (HPLC)

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COc1cc(cc(OC)c1OC)[C@H]1OC[C@H]2[C@@H]1CO[C@@H]2c1cc(OC)c(OC)c(OC)c1

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(-20℃)

With Ice Pack

≥ 2 years