Torachrysone-8-O-b-D-glucoside

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Torachrysone 8-O-glucoside 显示出 α-葡萄糖苷酶抑制活性，可用于治疗 2 型糖尿病。

Torachrysone 8-O-glucoside shows alpha-glucosidase inhibitory activities, it may be used for the management of type 2 diabetes.(In Vitro):A new kind of in vitro α±-glucosidase inhibition assay based on using maltose as the substrate was developed, and this new established method was used to determine the α±-glucosidase inhibitory activities of Polygonum multiflorum and four anthraquinone compounds. As a result, Polygonum multiflorum showed 50% α±-glucosidase inhibition at the concentration of 0.0032 mg mL-1 and four anthraquinone compounds including emodin, aloe-emodin, physcion and rhein showed strong α±-glucosidase inhibitory activities with IC50 values ranging from 4.12 μM to 5.68 μM, respectively. Moreover, the centrifugal ultrafiltration with LC-ESI-MSn was used to screen and identify active α±-glucosidase inhibitors from Polygonum multiflorum extract and nine small-molecule active compounds were successfully identified as potential α±-glucosidase inhibitors.

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Torachrysone 8-O-glucoside

Microbiology/Virology

Antifection

Anti-infection

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64032-49-1

408.403

C20H24O9

>98% (HPLC)

In Vitro:?DMSO : 50 mg/mL (122.43 mM)

COc1cc(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)c2c(O)c(C(C)=O)c(C)cc2c1

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(-20℃)

With Ice Pack

≥ 2 years