Robinetin

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Robinetin 具有抗氧化和抗自由基活性，高效抑制 EYPC 膜脂质过氧化和 HbA 糖基化。

Robinetin has antioxidant and antiradical activities, inhibits EYPC membrane lipid peroxidation and HbA glycosylation with high efficiency.(In Vitro):Robinetin inhibits the DNA synthesis in Proteus vulgaris, and the RNA synthesis in S. aureus. Robinetin exhibits photo-induced excited-state intramolecular proton transfer resulting in ‘two color’ (in ‘blue-violet’ and ‘yellow-green’ regions) fluorescence characteristic of flavonols, the relative contributions between the two colors being strongly modulated by the local environment of the fluorophore. Robinetin (0.1-10 μM; 1 h) inhibits HIV integrase cleavage and integration in a dose-dependent manner.(In Vivo):Pretreatment with 0.5, 12.5 or 25 mumol robinetin resulted in elevated induction of epidermal ODC by TPA at 6 h after TPA. However, treatment with 50 or 100 mumol robinetin diminished ODC induction at 6 h after TPA. Anti-mutagenicity was determined in the Salmonella typhimurium assay, Robinetin caused an 87% inhibition of mutagenicity by 2-aminoanthracene.

Robinetin (0.1-10 μM; 1 h) inhibits HIV integrase cleavage and integration in a dose-dependent manner.Robinetin inhibits the DNA synthesis in Proteus vulgaris, and the RNA synthesis in S. aureus.Robinetin (100-200 or 25 μM; 1 or 72 h) inhibitsegg yolk phosphatidylcholine (EYPC) membrane lipid peroxidation and hemoglobin A (HbA) glycosylation with high efficiency.Robinetin exhibits photo-induced excited-state intramolecular proton transfer resulting in ‘two color’ (in ‘blue-violet’ and ‘yellow-green’ regions) fluorescence characteristic of flavonols, the relative contributions between the two colors being strongly modulated by the local environment of the fluorophore.

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3,3',4',5',7-Pentahydroxyflavone

Microbiology/Virology

Antifection

Anti-infection

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490-31-3

302.238

C15H10O7

>98% (HPLC)

In Vitro:?DMSO : 120 mg/mL (397.04 mM)

Oc1ccc2c(c1)oc(-c1cc(O)c(O)c(O)c1)c(O)c2=O

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(-20℃)

With Ice Pack

≥ 2 years