Magnolioside

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

木兰苷具有抗疟原虫活性，对氯喹敏感的恶性疟原虫菌株具有显着的生长抑制活性。

Magnolioside has anti-plasmodial activity, shows notable growth inhibitory activity against chloroquine-sensitive strains of P. falciparum. It also shows a moderate antibacterial activity against Staphylococcus aureus CIP 53.154.Magnolioside exhibits significant neuroprotective activities against glutamate-induced toxicity.(In Vitro):Using antiplasmodial activity-guided fractionation, five coumarins, marmesinin (1), nodakenin (2), skimmin (3), apiosylskimmin (4), and Magnolioside (5), were isolated and evaluated for in vitro antiplasmodial activity, as well as for their cytotoxic potential on SK-OV-3 cancer cell lines. Compounds 1 and 5 showed notable growth inhibitory activity against chloroquine-sensitive strains of P. falciparum with IC(50) values of 5.3 and 8.2 μM. The compounds showed no significant cytotoxicity (IC(50) > 100 μM) toward the SK-OV-3 cancer cell line.

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Microbiology/Virology

Antifection

Anti-infection

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20186-29-2

354.311

C16H18O9

>98% (HPLC)

In Vitro:?DMSO : 50 mg/mL (141.12 mM)

COc1cc2oc(=O)ccc2cc1O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O

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(-20℃)

With Ice Pack

≥ 2 years