(2S)-2'-Methoxykurarinone

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

(2S)-2'-甲氧基苦参酮是从苦参 (Sophora flavescens) 的根中分离出来的。 (2S)-2'-Methoxykurarinone 具有抗炎、解热、抗糖尿病和抗肿瘤作用。

(2S)-2'-Methoxykurarinone is isolated from the roots of Sophora flavescens. (2S)-2'-Methoxykurarinone has anti-inflammatory, antipyretic, antidiabetic, and antineoplastic effects. (2S)-2'-Methoxykurarinone (MK) inhibits osteoclastogenesis and bone resorption through down-regulation of RANKL signaling. (2S)-2'-Methoxykurarinone (MK) displays cytotoxic activity against human myeloid leukemia HL-60 cells.(In Vitro):2'-Methoxykurarinone has strong alpha-glucosidase inhibitory activities, with IC(50) values of 155 microM. 2'-Methoxykurarinone is a noncompetitive inhibitor of protein tyrosine phosphatase 1B.

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2'-Methoxykurarinone | 2'-O-Methylkurarinone

Cytoskeleton/Cell Adhesion Molecules

Akt

Akt

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270249-38-2

452.547

C27H32O6

>98% (HPLC)

In Vitro:?DMSO : 25 mg/mL (55.24 mM)

COc1cc(O)ccc1[C@@H]1CC(=O)c2c(OC)cc(O)c(C[C@@H](CC=C(C)C)C(C)=C)c2O1

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(-20℃)

With Ice Pack

≥ 2 years