GSK-1520489A ( —— )

产品货号. M28990 CAS No. 1042433-41-9

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

GSK-1520489A
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

GSK-1520489A 是一种活性 PKMYT1 抑制剂。
产品描述

GSK-1520489A is an active PKMYT1 inhibitor.
体外实验

GSK-1520489A (4 μM, 24 h) treatment shows inhibition of phosphorylation of Tyr15 in Cdk1. Western Blot Analysis Cell Line:HT29 cells Concentration:4 μM Incubation Time:24 hours Result:Reduced Cdk1-phosphorylation at tyrosine in comparison to the uninhibited reaction.
体内实验

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同义词

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通路

Others
靶点

Other Targets
受体

MCT4
研究领域

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适应症

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1.Cluntun AA, et.al. The pyruvate-lactate axis modulates cardiac hypertrophy and heart failure. Cell Metab. 2021 Mar 2;33(3):629-648.e10.

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