021-51111890/在线客服
购物车（）
sales@molnova.cn
  • 咨询热线
    客服服务热线 13671568941/15317326293
  • 在线咨询
    963389683
  • 微信客服
    微信客服
  • 公众号
    扫码关注公众号
首页- Products - Others - Other Targets - BR102910?

BR102910?

CAS No. 2505339-54-6

BR102910? ( 4-Thiazolecarboxamide, N-[2-[(2S)-2-cyano-4,4-difluoro-1-pyrrolidinyl]-2-oxoethyl]-2-[(3,4-dichlorophenyl)methyl]- )

产品货号. M28937 CAS No. 2505339-54-6

4-噻唑甲酰胺，N-[2-[(2S)-2-氰基-4,4-二氟-1-吡咯烷基]-2-氧代乙基]-2-[(3,4-二氯苯基)甲基]-(BR102910)是成纤维细胞激活蛋白（FAP）的选择性抑制剂。

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ￥1805 有现货
10MG ￥2556 有现货
25MG ￥3646 有现货
50MG ￥4985 有现货
100MG ￥6372 有现货
200MG ￥8577 有现货
500MG 获取报价 有现货
1G 获取报价 有现货
1 mL x 10 mM in DMSO ￥2147 有现货
产品询价 大包装询价 加入购物车

生物学信息

  • 产品名称
    BR102910?
  • 注意事项
    本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
  • 产品简述
    4-噻唑甲酰胺，N-[2-[(2S)-2-氰基-4,4-二氟-1-吡咯烷基]-2-氧代乙基]-2-[(3,4-二氯苯基)甲基]-(BR102910)是成纤维细胞激活蛋白（FAP）的选择性抑制剂。
  • 产品描述
    4-Thiazolecarboxamide, N-[2-[(2S)-2-cyano-4,4-difluoro-1-pyrrolidinyl]-2-oxoethyl]-2-[(3,4-dichlorophenyl)methyl]-(BR102910) is a selective inhibitor of fibroblast activated protein (FAP).(In Vivo):4-Thiazolecarboxamide, N-[2-[(2S)-2-cyano-4,4-difluoro-1-pyrrolidinyl]-2-oxoethyl]-2-[(3,4-dichlorophenyl)methyl]-(C57BL/6J mice, 0-30 mg/kg, orally, once) showed significant FAP inhibition in a dose dependent manner .
  • 体外实验
    ——
  • 体内实验
    BR102910 (C57BL/6J mice, 0-30 mg/kg, Orally, once) shows significant FAP inhibition in a dose dependent manner. Animal Model:C57BL/6J mice (n = 5 per group)Dosage:0, 10 and 30 mg/kg Administration:Orally, once Result:Showed significant FAP inhibition in a dose dependent manner.
  • 同义词
    4-Thiazolecarboxamide, N-[2-[(2S)-2-cyano-4,4-difluoro-1-pyrrolidinyl]-2-oxoethyl]-2-[(3,4-dichlorophenyl)methyl]-
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    ——
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    2505339-54-6
  • 分子量
    459.3
  • 分子式
    C18H14Cl2F2N4O2S
  • 纯度
    >98% (HPLC)
  • 溶解度
    In Vitro:?DMSO : 100 mg/mL (217.72 mM)
  • SMILES
    O=C(C1=CSC(CC2=CC=C(Cl)C(Cl)=C2)=N1)NCC(N3[C@@H](C#N)CC(F)(F)C3)=O
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Wang GR, et al. New flavonoids with 2BS cell proliferation promoting effect from the seeds of Trigonella foenum-graecum L. J Nat Med. 2010 Jul;64(3):358-61.
计算器

浓度计算器

摩尔计算器

分子量计算器

产品手册
关联产品

  • (±)8(9)-EpETE

    Eicosapentaenoic acid is converted to epoxyeicosatetraenoic acids (EpETEs) by several cytochrome P450 isoforms. The major product of this epoxygenase pathway, (±)17(18)-EpETE , relaxes vascular and airway smooth muscle by activating large conductance Ca2+-activated K+ (BKCa) channels by directly interacting with BKα channel subunits. (±)8(9)-EpETE is an epoxygenase pathway product produced from EPA by CYP450 both in vitro and in vivo. The biological actions and physiological effects of this epoxide remain to be determined.

  • Tuberosin

    Tuberosin shows anti-inflammatory and antioxidant activities.It demonstrated a significantly potent inhibition on yeast α-glucosidase in a dose dependent manner.

  • SBE 13 hydrochloride

    SBE13 盐酸盐是一种有效且特异性的 PLK1 抑制剂 (IC50: 0.2 nM)；对 Aurora A 激酶、Plk2/3 没有抑制作用。

登录 注册