GPI-1485

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

GPI-1485 (GM1485) 是一种非免疫抑制性免疫亲和素配体，可促进中风后神经功能的改善和神经再生。

GPI-1485 (GM1485) is a nonimmunosuppressive immunophilin ligand, promoting neurofunctional improvement and neural regeneration following stroke.(In Vitro):GPI-1485 induced cellular reprogramming and neural cell induction in normal human dermal fibroblasts (NHDF) .(In Vivo):GPI-1485 (5 mg/kg; intraperitoneal injection; 6-week period of daily) improved long-term neurological recovery in rats

GPI-1485 (GM1485; 100 μM) induces cellular reprogramming and neural cell induction in normal human dermal fibroblasts (NHDF). Cell Viability Assay Cell Line:Normal human dermal fibroblasts (NHDF)Concentration:100 μM Incubation Time:Result:Induced cellular reprogramming and neural cell induction.

GPI-1485 (GM1485; 5 mg/kg; intraperitoneal injection; 6-week period of daily) improves long-term neurological recovery in rats. Animal Model:Adult male Wistar rats, weighing 250-300 g Dosage:5 mg/kg Administration:Intraperitoneal injection; daily; for a total of 42 days Result:Administration improved neurological function and is consistent with an upregulation of endogenous neurogenesis following stroke in rats.

GM1485

Others

Other Targets

USP8

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186268-78-0

241.287

C12H19NO4

>98% (HPLC)

In Vitro:?DMSO : 100 mg/mL (414.46 mM)

CCC(C)(C)C(=O)C(=O)N1CCC[C@H]1C(O)=O

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(-20℃)

With Ice Pack

≥ 2 years