VPC-80051 racemate ( VPC-80051 )

产品货号. M28584 CAS No. 877969-69-2

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

VPC-80051 racemate
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

VPC-80051是第一个利用计算机辅助药物发现方法抑制hnRNP A1剪接活性的小分子抑制剂。
产品描述

VPC-80051 is the first small molecule inhibitor of hnRNP A1 splicing activity by using a computer-aided drug discovery approach.(In Vitro):VPC-80051 interacts directly with hnRNP A1 RBD and reduces AR-V7 messenger levels in 22Rv1 CRPC cell line.
体外实验

VPC-80051 interacts directly with hnRNP A1 RBD and reduces AR-V7 messenger levels in 22Rv1 CRPC cell line. hnRNP A1 is a multifunctional RNA-binding protein that regulates alternative pre-mRNA splicing, transcription, nucleocytoplasmic shuttling, miRNA processing, and telomere elongation maintenance, as well as translation of cellular transcripts both in physiological and pathological conditions.
体内实验

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同义词

VPC-80051
通路

Others
靶点

Other Targets
受体

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研究领域

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适应症

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1.Fan X, Xu NJ, Shi JG. Bromophenols from the red alga Rhodomela confervoides. J Nat Prod. 2003 Mar;66(3):455-8.

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