Unifiram

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Unifiram 是一种认知增强剂。 Unifiram 诱导大鼠海马 CA1 区场兴奋性突触后电位 (fEPSP) 振幅持久增加 (EC50= 27 nM)，并增加大鼠大脑皮层乙酰胆碱 (ACh) 的释放。

Unifiram is a cognition-enhancer. Unifiram induces a long-lasting increase in the amplitude of field excitatory postsynaptic potentials (fEPSPs) in the rat hippocampal CA1 region (EC50= 27 nM) and increases acetylcholine (ACh) release in the rat cerebral cortex.(In Vivo):Unifiram (0.1 mg kg?1 i.p.) was able to prevent amnesia induced by scopolamine (0.8 mg kg?1 i.p.) in the rat Morris watermaze test. In the rat social learning test, Unifiram (0.1 mg kg?1 i.p.) injected in adults rats reduced the duration of active exploration of the familiar partner in the second session of the test. Unifiram, similarly to piracetam, reduced the duration of hypnosis induced by pentobarbital. At the highest effective doses, the investigated compound did not impair motor coordination (rota rod test), nor modified spontaneous (Animex).

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Others

Other Targets

15-PGDH

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272786-64-8

298.33

C13H15FN2O3S

>98% (HPLC)

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Fc1ccc(cc1)S(=O)(=O)N1CCN2C(CCC2=O)C1

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(-20℃)

With Ice Pack

≥ 2 years