λ-Cyhalothrin

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

高效氯氟氰菊酯是一种高效、广谱 II 型合成拟除虫菊酯杀虫剂，含有 α-氰基。高效氯氟氰菊酯可在多种应用中用于控制多种害虫。高效氯氟氰菊酯是一种针对钠通道的神经毒素存在于中枢神经系统神经元膜中。

lambda-Cyhalothrin is a high efficiency, broad-spectrum type II synthetic pyrethroid insecticide containing α-cyano group.lambda-Cyhalothrin is used to control a wide range of pests in a variety of applications.lambda-Cyhalothrin is a neurotoxin that targets sodium channels in the membranes of neurons in the central nervous system.(In Vitro):The mechanism of λ-Cyhalothrin toxicity produces delay in sodium channel inactivation, which leads to persistent depolarization of the nerve membrane. λ-Cyhalothrin produces membrane depolarization, calcium ion infl ux, and neurotransmitter release from rat brain synaptosomes.λ-Cyhalothrin possesses estrogenic properties and has an ability to function as a xenoestrogen promoting human breast carcinoma cell proliferation in vitro.λ-Cyhalothrin has found multiple uses in pest (fleas, cockroaches, flies, and ants) control.λ-Cyhalothrin is highly effective against the malaria transmitting species of Anopheles.(In Vivo):The effect of λ-Cyhalothrin (i.p.) on memory, movement activity, and co-ordination in mice exposed to bilateral clamping of the carotid arteries (BCCA) is investigated. Neither memory nor movement co-ordination are impaired by BCCA or λ-Cyhalothrin. Exploratory locomotor activity is significantly reduced in the BCCA/LCH group. Spontaneous movement activity is significantly reduced in the BCCA/λ-Cyhalothrin group . Exposure to λ-Cyhalothrin coexisting with BCCA decreases motor activity in the mice in 2 subsequent 30-min.

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Icon | Karate | lambda-Cyhalothrin

Membrane Transporter/Ion Channel

Sodium Channel

Angiotensin-converting Enzyme (ACE)

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91465-08-6

449.85

C23H19ClF3NO3

>98% (HPLC)

In Vitro:?DMSO : 33.33 mg/mL (74.09 mM)

CC1(C)[C@H](\C=C(/Cl)C(F)(F)F)[C@@H]1C(=O)O[C@@H](C#N)c1cccc(Oc2ccccc2)c1

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(-20℃)

With Ice Pack

≥ 2 years