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TRAM 39
CAS No. 197525-99-8
TRAM 39 ( 2-(2-chlorophenyl)-2,2-diphenylacetonitrile | 2-Chloro-alpha,alpha-diphenylbenzeneacetonitrile | TRAM-39 | ZINC27105797 )
产品货号. M27729 CAS No. 197525-99-8
TRAM 39 是中等电导 Ca2+ 激活的 K+ 通道的选择性阻断剂。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 2MG | ￥377 | 有现货 |
|
| 5MG | ￥677 | 有现货 |
|
| 10MG | ￥1026 | 有现货 |
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| 25MG | ￥1507 | 有现货 |
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| 50MG | ￥2074 | 有现货 |
|
| 100MG | ￥3357 | 有现货 |
|
| 500MG | ￥7092 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称TRAM 39
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述TRAM 39 是中等电导 Ca2+ 激活的 K+ 通道的选择性阻断剂。
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产品描述TRAM 39 is a selective blocker of intermediate-conductance Ca2+-activated K+channels.(In Vitro):In coeliac neurons, TRAM 39 depressed the amplitude of the prolonged conductance underlying the slow afterhyperpolarization, (gKCa2) by 57%.
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体外实验TRAM-39 (1 μM) reduces the peak amplitude of gKCa2 in sympathetic LAH neurons (mean percentage change 56%) in BAE cells.TRAM-39 (200 nM) diminishes lipopolysaccharide (LPS)-induced cryptdin release from paneth cells.
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体内实验TRAM-39 (1 μM; adds to the perfusate) fully blocks all IKCa channels in multicellular preparations.
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同义词2-(2-chlorophenyl)-2,2-diphenylacetonitrile | 2-Chloro-alpha,alpha-diphenylbenzeneacetonitrile | TRAM-39 | ZINC27105797
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通路Cell Cycle/DNA Damage
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靶点Potassium Channel
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受体——
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研究领域——
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适应症——
化学信息
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CAS Number197525-99-8
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分子量303.79
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分子式C20H14ClN
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纯度>98% (HPLC)
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溶解度In Vitro:?DMSO : 50 mg/mL (164.59 mM)
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SMILESClc1ccccc1C(C#N)(c1ccccc1)c1ccccc1
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Chang W, et al. Pd-Catalyzed regioselective hydroesterification of 2-allylphenols to seven-membered lactones without external CO gas. Org Biomol Chem. 2016 Mar 21;14(11):3047-52.
产品手册
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