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RS 67333 hydrochloride
CAS No. 168986-60-5
RS 67333 hydrochloride ( RS 67333 HCl | RS 67333 (hydrochloride) )
产品货号. M27698 CAS No. 168986-60-5
有效且高选择性的 5-HT4 部分激动剂。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥256 | 有现货 |
|
| 10MG | ￥421 | 有现货 |
|
| 25MG | ￥958 | 有现货 |
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| 50MG | ￥1451 | 有现货 |
|
| 100MG | ￥2142 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
| 1 mL x 10 mM in DMSO | ￥219 | 有现货 |
|
生物学信息
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产品名称RS 67333 hydrochloride
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述有效且高选择性的 5-HT4 部分激动剂。
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产品描述potent and highly selective 5-HT4 partial agonist.(In Vitro):RS 67333 hydrochloride exhibits affinities for the sigma 1 (pKi = 8.9) and sigma 2 (pKi = 8.0) binding sites. At the 5-HT4 receptor mediating relaxation of the carbachol-precontracted oesophagus, RS 67333 hydrochloride acts as a potent (pEC50 of 8.4), partial agonists (intrinsic activities, with respect to 5-HT is 0.5) with respect to 5-HT .
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体外实验RS 67333 hydrochloride does exhibit affinities for the sigma 1 (pKi = 8.9) and sigma 2 (pKi = 8.0) binding sites. At the 5-HT4 receptor mediating relaxation of the carbachol-precontracted oesophagus, RS 67333 hydrochloride acts as a potent (pEC50 of 8.4), partial agonists (intrinsic activities, with respect to 5-HT is 0.5) with respect to 5-HT.
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体内实验——
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同义词RS 67333 HCl | RS 67333 (hydrochloride)
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通路Others
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靶点Other Targets
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受体c-Fgr|Lyn|Hck|Apoptosis
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研究领域——
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适应症——
化学信息
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CAS Number168986-60-5
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分子量389.36
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分子式C19H30Cl2N2O2
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纯度>98% (HPLC)
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溶解度In Vitro:?DMSO : 50 mg/mL (128.42 mM)
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SMILESCl.CCCCN1CCC(CCC(=O)c2cc(Cl)c(N)cc2OC)CC1
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Weir MC, et al. Selective Inhibition of the Myeloid Src-Family Kinase Fgr Potently Suppresses AML Cell Growth in Vitro and in Vivo. ACS Chem Biol. 2018 Jun 15;13(6):1551-1559.
产品手册
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