(S,R,S)-AHPC-PEG2-NH2

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

(S,R,S)-AHPC-PEG2-NH2 (VH032-PEG2-NH2) 是一种合成的 E3 连接酶配体-接头缀合物，包含基于 (S,R,S)-AHPC 的 VHL 配体和 2 单元 PEG 接头用于合成PROTAC。

(S,R,S)-AHPC-PEG2-NH2 (VH032-PEG2-NH2) is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 2-unit PEG linker used in the synthesis of PROTACs.(In Vitro):PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

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VH032-PEG2-NH2 | VHL Ligand-Linker Conjugates 3 | E3 ligase Ligand-Linker Conjugates 6 Free Base

Others

Other Targets

σ1

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2010159-60-9

575.72

C28H41N5O6S

>98% (HPLC)

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O=C([C@H]1N(C([C@@H](NC(COCCOCCN)=O)C(C)(C)C)=O)C[C@H](O)C1)NCC2=CC=C(C3=C(C)N=CS3)C=C2

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(-20℃)

With Ice Pack

≥ 2 years