Biotin-PEG12-NHS ester
CAS No. 1934296-88-4
Biotin-PEG12-NHS ester ( —— )
产品货号. M26902 CAS No. 1934296-88-4
Biotin-PEG12-NHS 酯是一种基于 PEG 的 PROTAC 连接体,可用于 PROTAC 的合成。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ¥522 | 有现货 |
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| 10MG | ¥769 | 有现货 |
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| 25MG | ¥1256 | 有现货 |
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| 50MG | ¥1879 | 有现货 |
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| 100MG | ¥2547 | 有现货 |
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| 200MG | ¥3609 | 有现货 |
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| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
| 1 mL x 10 mM in DMSO | ¥828 | 有现货 |
|
生物学信息
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产品名称Biotin-PEG12-NHS ester
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述Biotin-PEG12-NHS 酯是一种基于 PEG 的 PROTAC 连接体,可用于 PROTAC 的合成。
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产品描述Biotin-PEG12-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.(In Vitro):PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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体外实验PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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体内实验——
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同义词——
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通路Others
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靶点Other Targets
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受体Arf1| Arf6
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研究领域——
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适应症——
化学信息
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CAS Number1934296-88-4
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分子量941.1
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分子式C41H72N4O18S
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纯度>98% (HPLC)
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溶解度In Vitro:?DMSO : 100 mg/mL (106.26 mM)
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SMILES[H][C@]12CS[C@@H](CCCCC(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(=O)ON3C(=O)CCC3=O)[C@@]1([H])NC(=O)N2
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Benabdi S, et al. Family-wide Analysis of the Inhibition of Arf Guanine Nucleotide Exchange Factors with Small Molecules: Evidence of Unique Inhibitory Profiles. Biochemistry. 2017 Sep 26;56(38):5125-5133.
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