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Telratolimod
CAS No. 1359993-59-1
Telratolimod ( MEDI9197 | 3M-052 )
产品货号. M26840 CAS No. 1359993-59-1
Telratolimod 是一种 Toll 样受体 7/8 激动剂。它具有抗肿瘤活性。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 2MG | ￥2024 | 有现货 |
|
| 5MG | ￥3411 | 有现货 |
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| 10MG | ￥4931 | 有现货 |
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| 25MG | ￥7366 | 有现货 |
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| 50MG | ￥10137 | 有现货 |
|
| 100MG | ￥13230 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Telratolimod
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述Telratolimod 是一种 Toll 样受体 7/8 激动剂。它具有抗肿瘤活性。
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产品描述Telratolimod is a toll-like receptors 7/8 agonist. It has an antitumor activity.(In Vivo):Telratolimod (50 μg) suppresses the tumor volume and more effectively blocks tumor growth in combination with CpG ODN in BALB/c mice bearing CT26 colon carcinoma cells. Telratolimod (100 μg) plus 200 μg of CpG ODN slows tumor growth and prolongs the survival of mice bearing large tumors .
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体外实验Telratolimod (3M-052) is a toll like receptors 7/8 (TLR7/8) agonist, with antitumor activity.
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体内实验Telratolimod (50 μg) inhibits the tumor volume, and more potently blocks tumor gowth in combination with CpG ODN in BALB/c mice bearing CT26 colon carcinoma cells. Telratolimod (100 μg) plus 200 μg of CpG ODN slows tumor growth and prolongs survival of mice bearing large tumors.
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同义词MEDI9197 | 3M-052
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通路Immunology/Inflammation
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靶点TLR
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受体LpxC
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研究领域——
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适应症——
化学信息
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CAS Number1359993-59-1
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分子量593.901
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分子式C36H59N5O2
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纯度>98% (HPLC)
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溶解度In Vitro:?DMSO : 62.5 mg/mL (105.24 mM)
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SMILESCCCCCCCCCCCCCCCCCC(=O)NCCCCOn1c(CCCC)nc2c(N)nc3ccccc3c12
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Ushiyama F, et al. Lead optimization of 2-hydroxymethyl imidazoles as non-hydroxamate LpxC inhibitors: Discovery of TP0586532. Bioorg Med Chem. 2021;30:115964.
产品手册
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