Radezolid ( RX-1741 )

产品货号. M26804 CAS No. 869884-78-6

Radezolid 是一种新型恶唑烷酮类抗生素。

纯度: >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

规格	价格/人民币	库存	数量
5MG	￥785	有现货
10MG	￥1492	有现货
25MG	￥2623	有现货
50MG	￥3683	有现货
100MG	￥5067	有现货
500MG	获取报价	有现货
1G	获取报价	有现货
1 mL x 10 mM in DMSO	￥756	有现货

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生物学信息

产品名称

Radezolid
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Radezolid 是一种新型恶唑烷酮类抗生素。
产品描述

Radezolid is a novel oxazolidinone antibiotic agent.(In Vitro):Radezolid displays a greater potency than linezolid, independent of the bacteria tested, when concentrations are expressed on a weight (mg/L) basis. Radezolid shows an improved potency compared to that of linezolid when concentrations are expressed on a weight (mg/L) basis. Radezolid MICs are systematically equal to or lower (up to 3 log2 dilutions) than those of linezolid for all linezolid-susceptible strains, with an 8-fold difference for the linezolid-resistant strains. Radezolid and TR-700 perform well against 3-copy G2447T, G2576T, and G2576T/T2571C mutants .
体外实验

Radezolid MICs are systematically equal to or lower (up to 3 log2 dilutions) than those of linezolid for all linezolid-susceptible strains, with an 8-fold difference for the linezolid-resistant strains. Radezolid shows a greater potency than linezolid, independent of the bacteria tested, when concentrations are expressed on a weight (mg/L) basis. Radezolid shows an improved potency compared to that of linezolid when concentrations are expressed on a weight (mg/L) basis. Radezolid and TR-700 perform well against 3-copy G2447T, G2576T, and G2576T/T2571C mutants.
体内实验

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同义词

RX-1741
通路

GPCR/G Protein
靶点

Antibacterial
受体

TNIK
研究领域

——
适应症

——

化学信息

CAS Number

869884-78-6
分子量

438.463
分子式

C22H23FN6O3
纯度

>98% (HPLC)
溶解度

In Vitro:?DMSO : ≥ 25 mg/mL (57.02 mM)
SMILES

CC(=O)NC[C@H]1CN(C(=O)O1)c1ccc(c(F)c1)-c1ccc(CNCc2cnn[nH]2)cc1
化学全称

——

运输与储存

储存条件

(-20℃)
运输条件

With Ice Pack
稳定性

≥ 2 years

参考文献

1.Lee Y, et al. Synergistic inhibition effect of TNIK inhibitor KY-05009 and receptor tyrosine kinase inhibitor dovitinib on IL-6-induced proliferation and Wnt signaling pathway in human multiple myeloma cells. Oncotarget. 2017 Jun 20;8(25):41091-41101.

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