Pranidipine

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

普拉地平是一种新型长效 1,4-二氢吡啶钙通道阻滞剂。

Pranidipine is a novel, long-acting 1,4-dihydropyridine calcium channel blocker. It prolongs acetylcholine-induced relaxation in presence of endothelium as well as nitroglycerin-induced relaxation in absence of endothelium. It also has antihypertensive activity.(In Vivo):Pranidipine enhances cyclic GMP-dependent nitric oxide-induced relaxation of rat aorta.

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OPC-13340

GPCR/G Protein

Calcium Channel

Autophagy| mTORC1

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99522-79-9

448.475

C25H24N2O6

>98% (HPLC)

In Vitro:?DMSO : 270 mg/mL (602.05 mM)

COC(=O)C1=C(C)NC(C)=C(C1c1cccc(c1)[N+]([O-])=O)C(=O)OC\C=C\c1ccccc1

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(-20℃)

With Ice Pack

≥ 2 years