ON-013100

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

ON-013100 是一种抗肿瘤药。 ON-013100 还充当有丝分裂抑制剂，可以抑制 Cyclin D1 的表达。

ON-013100 is an antineoplastic drug. ON-013100 also acts as a mitotic inhibitor that could inhibit Cyclin D1 expression.(In Vitro):ON 013100 inhibits the proliferation of MCL (JEKO-1 and MINO), breast (MCF7 and MDA-MB-231), gastric (AGS), and esophageal (OE19, OE33, and FLO-1) cancer cell lines at a nanomolar concentration (ON 013100 GI50=6.7-11.2 nM). ON013100 significantly alters the cell cycle profile, dramatically increasing the number of cells in the G2/M phase. Treatment of the cells with even 0.1 μM of ON013100 results in an arrest of the G2/M phase of the cell cycle. ON-013100 induces apoptosis and has activity against most human cancer cell lines in vitro.

ON-013100 induces apoptosis, and has activity against most human cancer cell lines in vitro. ON013100 significantly alters the cell cycle profile, dramatically increasing the number of cells in G2/M phase. Treatment of the cells with even 0.1 μM of ON013100 results in an arrest of the G2/M phase of the cell cycle. ON 013100 inhibits the proliferation of MCL (JEKO-1 and MINO), breast (MCF7 and MDA-MB-231), gastric (AGS), and esophageal (OE19, OE33, and FLO-1) cancer cell lines at a nanomolar concentration (ON 013100 GI50=6.7-11.2 nM) .

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Angiogenesis

CDK

Sweet taste receptor

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865783-95-5

394.44

C19H22O7S

>98% (HPLC)

In Vitro:?DMSO : 25 mg/mL (63.38 mM)

COc1cc(OC)c(\C=C\S(=O)(=O)Cc2ccc(OC)c(O)c2)c(OC)c1

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(-20℃)

With Ice Pack

≥ 2 years