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N,N'-Diacetyl-L-cystine

CAS No. 5545-17-5

N,N'-Diacetyl-L-cystine ( DiNAC )

产品货号. M26768 CAS No. 5545-17-5

N,N'-二乙酰-L-胱氨酸是 N-乙酰半胱氨酸的二硫化物二聚体,具有免疫调节特性。

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
50MG ¥116 有现货
100MG ¥156 有现货
500MG ¥366 有现货
1G 获取报价 有现货
1 mL x 10 mM in DMSO ¥181 有现货

生物学信息

  • 产品名称
    N,N'-Diacetyl-L-cystine
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    N,N'-二乙酰-L-胱氨酸是 N-乙酰半胱氨酸的二硫化物二聚体,具有免疫调节特性。
  • 产品描述
    N,N'-Diacetyl-L-cystine is the disulphide dimer of N-acetylcysteine with immunomodulating properties. N,N'-diacetyl-L-cystine also has antiatherosclerotic effects in Watanabe-heritable hyperlipidemic rabbit (WHHL) rabbits. N,N'-diacetyl-L-cystine is also an effective and orally active modulator of contact sensitivity/delayed-type hypersensitivity reactions in rodents.(In Vivo):N,N'-Diacetyl-L-cystine (DiNAC; 0-973.11 μg/kg; p.o.; daily; for 12 weeks; WHHL rabbits) treatment decreases by 50% thoracic aorta atherosclerosis. However, it has no affecting plasma lipid levels.
  • 体外实验
    ——
  • 体内实验
    N,N'-Diacetyl-L-cystine (DiNAC; 0-973.11 μg/kg; oral administration; daily; for 12 weeks; WHHL rabbits) treatment reduces by 50% thoracic aorta atherosclerosis, without affecting plasma lipid levels. Animal Model:Male heritable hyperlipidemic rabbit (WHHL) rabbits (10-22 weeks) Dosage:0 μg/kg, 9.73 μg/kg, or 973.11 μg/kg Administration:Oral administration; daily; for 12 weeks Result:Reduced by 50% thoracic aorta atherosclerosis, without affecting plasma lipid levels.
  • 同义词
    DiNAC
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    CDK4/CyclinD1| CDK6/CyclinD3
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    5545-17-5
  • 分子量
    324.37
  • 分子式
    C10H16N2O6S2
  • 纯度
    >98% (HPLC)
  • 溶解度
    In Vitro:?DMSO : 125 mg/mL (385.36 mM)
  • SMILES
    O=C(O)[C@H](CSSC[C@@H](C(O)=O)NC(C)=O)NC(C)=O
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.1. Ping Chen, et al. 2-amino-pyridine or 2-amino-pyrimidine derivatives as cyclin dependent kinase inhibitors. WO2019207463A1.
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