Methoprene
CAS No. 40596-69-8
Methoprene ( ZR-515 )
产品货号. M26753 CAS No. 40596-69-8
Methoprene 是一种保幼激素 (JH) 模拟物和生物农药。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 2MG | ¥136 | 有现货 |
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| 5MG | ¥199 | 有现货 |
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| 10MG | ¥275 | 有现货 |
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| 25MG | ¥430 | 有现货 |
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| 50MG | ¥619 | 有现货 |
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| 100MG | ¥753 | 有现货 |
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| 500MG | ¥1782 | 有现货 |
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| 1G | 获取报价 | 有现货 |
|
| 1 mL x 10 mM in DMSO | ¥264 | 有现货 |
|
生物学信息
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产品名称Methoprene
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述Methoprene 是一种保幼激素 (JH) 模拟物和生物农药。
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产品描述Methoprene is a juvenile hormone (JH) mimic and a biological pesticide. Methoprene acts as an insect growth regulator interfering with the lifecycles of insects and preventing insects from reaching maturity or reproducing.(In Vivo):The time of first brood deposition is affected by methoprene, with a clear concentration-dependent response and a NOEC of 32 nM. Methoprene reduces fecundity according to a 2-segmented line, with thresholds of 24 and < or =0.18 nM. Methoprene reduces the growth rate of daphnids with evidence of only a single concentration-response line, having a threshold of 12.6 nM. Molt frequency is reduced by methoprene in a concentration-dependent manner, with a response curve corresponding to a 2-segmented line and thresholds at 4.2 and 0.21 nM.
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体外实验Methoprene reduces the growth rate of daphnids with evidence of only a single concentration-response line, having a threshold of 12.6 nM. Molt frequency is reduced by methoprene in a concentration-dependent manner, with a response curve corresponding to a 2-segmented line and thresholds at 4.2 and 0.21 nM. An endpoint related to reproductive maturation, the time of first brood deposition, is also affected by methoprene, with a clear concentration-dependent response and a NOEC of 32 nM. Methoprene reduces fecundity according to a 2-segmented line, with thresholds of 24 and < or =0.18 nM. Methoprene elicits significant toxicity to endocrine-related processes in the 5-50 nM concentration range.
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体内实验——
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同义词ZR-515
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通路Others
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靶点Other Targets
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受体E3 Ligase Ligand-Linker Conjugate
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研究领域——
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适应症——
化学信息
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CAS Number40596-69-8
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分子量310.478
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分子式C19H34O3
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纯度>98% (HPLC)
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溶解度In Vitro:?Ethanol : 100 mg/mL (322.09 m)
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SMILESCOC(C)(C)CCCC(C)C\C=C\C(\C)=C\C(=O)OC(C)C
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
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