N-(2-Hydroxypropyl)methacrylamide ( —— )

产品货号. M26312 CAS No. 21442-01-3

COA

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HNMR

HPLC

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产品名称

N-(2-Hydroxypropyl)methacrylamide
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

N-(2-羟丙基)甲基丙烯酰胺用于合成共聚物，用于在内脏利什曼病中靶向递送抗利什曼原虫化合物。
产品描述

N-(2-Hydroxypropyl)methacrylamide is used in the synthesis of copolymers for the targeted delivery of antileishmanial agents in Visceral leishmaniasis.(In Vivo):N-(2-Hydroxypropyl)methacrylamide copolymer-drug conjugates (5 mg/kg) contains lysosomally degradable side chains and shows significant antileishmanial activity (>99% inhibition) in vivo .
体外实验

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体内实验

At 5 mg/kg body weight drug equivalent dose, all N-(2-Hydroxypropyl)methacrylamide copolymer-drug conjugates which contained lysosomally degradable side chains shows significant in vivo antileishmanial activity (>99% inhibition).
同义词

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通路

Microbiology/Virology
靶点

Parasite
受体

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研究领域

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适应症

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1.Li Y, Wang CL, Guo SX, Yang JS, Xiao PG. Two new compounds from Dendrobium candidum. Chem Pharm Bull (Tokyo). 2008 Oct;56(10):1477-9.

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