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hDHODH-IN-1
CAS No. 1173715-42-8
hDHODH-IN-1 ( —— )
产品货号. M26247 CAS No. 1173715-42-8
hDHODH-IN-1 是一种人二氢乳清酸脱氢酶 (hDHODH) 抑制剂，具有抗炎作用。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥658 | 有现货 |
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| 10MG | ￥1055 | 有现货 |
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| 25MG | ￥1693 | 有现货 |
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| 50MG | ￥2399 | 有现货 |
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| 100MG | ￥3123 | 有现货 |
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| 200MG | ￥4113 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
| 1 mL x 10 mM in DMSO | ￥725 | 有现货 |
|
生物学信息
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产品名称hDHODH-IN-1
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述hDHODH-IN-1 是一种人二氢乳清酸脱氢酶 (hDHODH) 抑制剂，具有抗炎作用。
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产品描述hDHODH-IN-1 is an inhibitor of human dihydroorotate dehydrogenase (hDHODH) with an anti-inflammatory effect.(In Vitro):Dihydroorotate dehydrogenase (DHODH) is a class-2 dihydroorotate dehydrogenase in human.?Inhibitors have been developed to eliminate human DHODH (hDHODH) activity, which is associated with cancers,inflammatory diseases , and autoimmune and multiple sclerosis because DHODH is required to ensure proliferating-cell viability.
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体外实验Human dihydroorotate dehydrogenase (hDHODH) is a class-2 dihydroorotate dehydrogenase. Because DHODH is required to ensure proliferating-cell viability, inhibitors have been developed to eliminate human DHODH (hDHODH) activity, which is associated with cancers, multiple sclerosis, and autoimmune and inflammatory diseases.
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体内实验——
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同义词——
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通路Metabolic Enzyme/Protease
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靶点Dehydrogenase
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受体PEGs
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研究领域——
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适应症——
化学信息
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CAS Number1173715-42-8
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分子量278.311
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分子式C17H14N2O2
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纯度>98% (HPLC)
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溶解度In Vitro:?DMSO : 250 mg/mL (898.28 mM)
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SMILESC\C(O)=C(/C#N)C(=O)Nc1ccc(cc1)-c1ccccc1
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
