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Ca2+ channel agonist 1
CAS No. 1402821-24-2
Ca2+ channel agonist 1 ( —— )
产品货号. M26083 CAS No. 1402821-24-2
Ca2+ 通道激动剂 1 是 N 型 Ca2+ 通道的激动剂和 Cdk2 的抑制剂（EC50：14.23 μM 和 3.34 μM），可用作运动神经末梢功能障碍的潜在治疗方法。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥1644 | 有现货 |
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| 10MG | ￥2366 | 有现货 |
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| 25MG | ￥3646 | 有现货 |
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| 50MG | ￥4976 | 有现货 |
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| 100MG | ￥6588 | 有现货 |
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| 200MG | ￥8892 | 有现货 |
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| 500MG | 获取报价 | 有现货 |
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| 1G | 获取报价 | 有现货 |
|
| 1 mL x 10 mM in DMSO | ￥1321 | 有现货 |
|
生物学信息
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产品名称Ca2+ channel agonist 1
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述Ca2+ 通道激动剂 1 是 N 型 Ca2+ 通道的激动剂和 Cdk2 的抑制剂（EC50：14.23 μM 和 3.34 μM），可用作运动神经末梢功能障碍的潜在治疗方法。
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产品描述Ca2+ channel agonist 1 is an agonist of N-type Ca2+ channel and an inhibitor of Cdk2 (EC50s: 14.23 μM and 3.34 μM) and is used as a potential treatment for motor nerve terminal dysfunction.(In Vitro):Ca2+ channel agonist 1 (Compound 13d) exhibits a ca. 2-fold increased agonism and a 22-fold decreased cdk2 kinase activity versus the standard, (R)-roscovitine.
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体外实验Ca2+ channel agonist 1 (Compound 13d) is an agonist of N-type Ca2+ channel and an inhibitor of Cdk2, with EC50s of 14.23 μM and 3.34 μM, respectively. Ca2+ channel agonist 1 exhibits a ca. 2-fold increased agonism and a 22-fold decreased cdk2 kinase activity versus the standard, (R)-roscovitine.
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体内实验——
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同义词——
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通路GPCR/G Protein
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靶点Calcium Channel
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受体Apoptosis| NF-κB
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研究领域——
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适应症——
化学信息
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CAS Number1402821-24-2
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分子量354.458
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分子式C19H26N6O
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纯度>98% (HPLC)
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溶解度In Vitro:?DMSO : 50 mg/mL (141.06 mM)
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SMILESCCCn1cnc2c(NCc3ccccc3)nc(N[C@H](CC)CO)nc12
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Cho K, et al. Inhibition of TNF-α-Mediated NF-κB Transcriptional Activity by Dammarane-Type Ginsenosidesfrom Steamed Flower Buds of Panax ginseng in HepG2 and SK-Hep1 Cells. Biomol Ther (Seoul). 2014 Jan;22(1):55-61.
产品手册
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