p32 Inhibitor M36 ( —— )

产品货号. M25043 CAS No. 802555-85-7

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

p32 Inhibitor M36
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Asciminib (ABL001) 盐酸盐是一种有效的选择性变构 BCR-ABL1 抑制剂，可抑制 Ba/F3 细胞生长，IC50 为 0.25 nM。
产品描述

p32 Inhibitor M36 inhibits SF188 glioma cells proliferation (IC50 of 77.9 μM in complete media) and is much more potent under low glucose conditions with an IC50 of 7.3 μM.p32 Inhibitor M36 is selective for p32 overexpressing cells.p32 Inhibitor M36 is also a potent inhibitor of patient-derived neurospheres with an IC50 of 2.8 μM.
体外实验

p32 Inhibitor M36 inhibits SF188 glioma cells proliferation (IC50 of 77.9 μM in complete media) and is much more potent under low glucose conditions with an IC50 of 7.3 μM. p32 Inhibitor M36 is selective for p32 overexpressing cells.p32 Inhibitor M36 is also a potent inhibitor of patient-derived neurospheres with an IC50 of 2.8 μM.
体内实验

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同义词

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通路

Angiogenesis
靶点

PKC
受体

M36
研究领域

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适应症

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1. Yenugonda V,et al. A novel small molecule inhibitor of p32 mitochondrial protein overexpressed in glioma. J Transl Med. 2017 Oct 18;15(1):210.

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