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EG1

CAS No. 693241-54-2

EG1 ( —— )

产品货号. M24706 CAS No. 693241-54-2

EG1 是 Pax2 转录激活的新型特异性抑制剂,靶向 DNA 结合域并抑制胚胎肾脏发育。

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥491 有现货
10MG ¥791 有现货
25MG ¥1283 有现货
50MG ¥1925 有现货
100MG ¥2601 有现货
200MG ¥3519 有现货
500MG 获取报价 有现货
1G 获取报价 有现货
1 mL x 10 mM in DMSO ¥436 有现货

生物学信息

  • 产品名称
    EG1
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    EG1 是 Pax2 转录激活的新型特异性抑制剂,靶向 DNA 结合域并抑制胚胎肾脏发育。
  • 产品描述
    EG1, a novel specific inhibitor of Pax2 transcription activation, targets the DNA binding domain and inhibits embryonic kidney development.
  • 体外实验
    Cell Viability Assay Cell Line:Pax2 positive: a renal cell carcinoma line (RCC111), two ovarian carcinoma cell lines (TOV112D and ES-2); Pax2 negative: prostate cell lines 22Rv1, PC3 or the ovarian cancer cell line SK-OV-3 Concentration:0, 12.5, 25 μM Incubation Time:48 hours Result:All Pax2 positive cells exhibited a significant decrease in cell viability, whereas none of the Pax2 negative cells were affected.
  • 体内实验
    ——
  • 同义词
    ——
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    Pax2
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    693241-54-2
  • 分子量
    390.39
  • 分子式
    C22H18N2O5
  • 纯度
    >98% (HPLC)
  • 溶解度
    DMSO:70mg/ml(179.31mM; need ultrasonic)
  • SMILES
    COc(cccc1)c1C(Nc(cc1)ccc1C(Nc(cccc1)c1C(O)=O)=O)=O
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Smith CB, Phillips T, Smith TJ. Using the New ASCO Clinical Practice Guideline for Palliative Care Concurrent With Oncology Care Using the TEAM Approach. Am Soc Clin Oncol Educ Book. 2017;37:714-723. doi: 10.14694/EDBK_175474. PubMed PMID: 28561696.
产品手册
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