Thalidomide-5-OH
CAS No. 64567-60-8
Thalidomide-5-OH ( —— )
产品货号. M24660 CAS No. 64567-60-8
Thalidomide-5-OH 是基于 Thalidomide 的 cereblon 配体,用于招募 CRBN 蛋白。它可以通过连接子与蛋白质的配体连接,形成PROTAC。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 500MG | ¥97 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
| 1 mL x 10 mM in DMSO | ¥103 | 有现货 |
|
生物学信息
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产品名称Thalidomide-5-OH
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述Thalidomide-5-OH 是基于 Thalidomide 的 cereblon 配体,用于招募 CRBN 蛋白。它可以通过连接子与蛋白质的配体连接,形成PROTAC。
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产品描述Thalidomide-5-OH is the Thalidomide-based cereblon ligand that used in the recruitment of CRBN protein. It can be connected to the ligand for protein by a linker to form PROTAC.
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体外实验——
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体内实验——
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同义词——
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通路Others
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靶点Other Targets
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受体Others
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研究领域——
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适应症——
化学信息
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CAS Number64567-60-8
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分子量274.23
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分子式C13H10N2O5
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纯度>98% (HPLC)
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溶解度DMSO : 60 mg/mL (218.80 mM; Need ultrasonic)
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SMILESOc(cc1)cc(C(N2C(CCC(N3)=O)C3=O)=O)c1C2=O
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Megan G Marks, et al. Effects of Putative Hydroxylated Thalidomide Metabolites on Blood Vessel Density in the Chorioallantoic Membrane (CAM) Assay and on Tumor and Endothelial Cell Proliferation. Biol Pharm Bull. 2002 May;25(5):597-604.
产品手册
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