Acetoacetic acid sodium salt

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

乙酰乙酸钠盐是非酯化脂肪酸的代谢产物，参与人类糖尿病的发生。

Acetoacetic acid sodium salt is a metabolite of non-esterified fatty acids, involved in the development of human diabetes.

Acetoacetic acid sodium induces oxidative stress to inhibit the assembly of very low density lipoprotein in bovine hepatocytes.Acetoacetic acid (0.6, 2.4, 4.8 mM) increases malondialdehyde (MDA) content in high-dose group (GH) group, decreases mRNA expression of Mn SOD, Cu/Zn SOD, and glutathione peroxidase (GSH-Px) in all groups, lowers catalase (CAT) mRNA expression in medial-dose group (GM), and GH groups. In addition, Acetoacetic acid down-regulates the mRNA expression of apolipoprotein B100 (ApoB100), apolipoprotein E (ApoE), and low density lipoprotein receptor (LDLR). Thus, VLDL assembly is decreased andtriglyceride (TG) accumulation is increased in these bovine hepatocytes.

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Others

Other Targets

Others

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623-58-5

124.07

C4H5NaO3

>98% (HPLC)

H2O:50 mg/mL (403.00 mM; Need ultrasonic)

CC(=O)CC(=O)[O-].[Na+]

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(-20℃)

With Ice Pack

≥ 2 years