Euscaphic acid ( —— )

产品货号. M24506 CAS No. 53155-25-2

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

Euscaphic acid
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

桉树酸具有抗糖尿病和抗炎活性，它通过干扰 TRAF6 与 IRAK1 和 TAK1 的聚集，从而阻断 IKK 和 MAPK 信号转导的激活，从而下调 NF-κB 的激活，从而抑制 LPS 诱导的炎症反应。
产品描述

Euscaphic acid has anti-diabetic, and anti-inflammatory activities, it inhibits LPS-induced inflammatory responses by interference with the clustering of TRAF6 with IRAK1 and TAK1, resulting in blocking the activation of IKK and MAPKs signal transduction to downregulate NF-κB activations.
体外实验

Euscaphic acid induces apoptosis and cell cycle arrest in NPC cells by suppression of the PI3K/AKT/mTOR signaling pathway.
体内实验

——
同义词

——
通路

Immunology/Inflammation
靶点

NOS
受体

LDL|NO Synthase|PGE
研究领域

——
适应症

——

CAS Number

53155-25-2
分子量

488.7
分子式

C30H48O5
纯度

>98% (HPLC)
溶解度

In Vitro:?DMSO : 250 mg/mL (511.56 mM)
SMILES

C[C@@H]1CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)C[C@@H](O)[C@@H](O)C(C)(C)C5CC[C@@]34C)C2[C@]1(C)O)C(O)=O
化学全称

——

1.Mahmud S A . Anti-Contraction Effects of Euscaphic Acid Isolated from Crataegus azarolus var. aronia L on Rat’s Aortic Smooth Muscle. 2015.

计算器

产品手册

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