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AS 1269574
CAS No. 330981-72-1
AS 1269574 ( AS1269574 )
产品货号. M24268 CAS No. 330981-72-1
AS 1269574 是一种有效的口服 GPR119 激动剂。 AS1269574具有用于2型糖尿病研究的潜力。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥330 | 有现货 |
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| 10MG | ￥528 | 有现货 |
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| 25MG | ￥1014 | 有现货 |
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| 50MG | ￥1600 | 有现货 |
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| 100MG | ￥2331 | 有现货 |
|
| 200MG | ￥3402 | 有现货 |
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| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
| 1 mL x 10 mM in DMSO | ￥360 | 有现货 |
|
生物学信息
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产品名称AS 1269574
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述AS 1269574 是一种有效的口服 GPR119 激动剂。 AS1269574具有用于2型糖尿病研究的潜力。
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产品描述AS 1269574 is a potent, orally available GPR119 agonist. AS1269574 has the potential for the research of type 2 diabetes.
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体外实验——
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体内实验AS1269574 sgnificantly reduced the blood glucose AUC after 2 h (AUC0-2h) of administration. Animal Model:Eight-week-old ICR mice Dosage:100 mg/kg Administration:P.o.Result:Sgnificantly reduced the blood glucose AUC after 2 h (AUC0-2h) of administration. Similarly, plasma insulin AUC0-2h was significantly higher in the mice.
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同义词AS1269574
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通路Cell Cycle/DNA Damage
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靶点GPR
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受体GPR119|TRPA1
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研究领域——
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适应症——
化学信息
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CAS Number330981-72-1
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分子量308.18
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分子式C13H14BrN3O
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纯度>98% (HPLC)
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溶解度DMSO:250 mg/mL (811.24 mM; Need ultrasonic)
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SMILESCC1=CC(=NC(=N1)C2=CC=C(C=C2)Br)NCCO
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Yoshida S, et al. Identification of a novel GPR119 agonist, AS1269574, with in vitro and in vivo glucose-stimulated insulin secretion. Biochem Biophys Res Commun. 2010;400(3):437-441.
