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WR-99210
CAS No. 30711-93-4
WR-99210 ( 6,6-Dimethyl-1-[3-(2,4,5-trichlorophenoxy)propoxy]-1,6-dihydro-1,3,5-triazine-2,4-diamine | WR99210 hydrochloride(47326-86-3 free base) )
产品货号. M24237 CAS No. 30711-93-4
WR-99210 是恶性疟原虫二氢叶酸还原酶 (pfDHFR) 的有效抑制剂，而 pfDHFR 是主要的疟疾药物靶点。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥1226 | 有现货 |
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| 10MG | ￥1872 | 有现货 |
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| 25MG | ￥3097 | 有现货 |
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| 50MG | ￥4427 | 有现货 |
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| 100MG | ￥5967 | 有现货 |
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| 200MG | ￥8037 | 有现货 |
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| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
| 1 mL x 10 mM in DMSO | ￥1406 | 有现货 |
|
生物学信息
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产品名称WR-99210
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述WR-99210 是恶性疟原虫二氢叶酸还原酶 (pfDHFR) 的有效抑制剂，而 pfDHFR 是主要的疟疾药物靶点。
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产品描述WR-99210 is a potent inhibitor of?Plasmodium falciparum?dihydrofolate reductase (pfDHFR), which is a major malarial drug target. It has subnanomolar potency for the wild type, double mutant and quadruple mutant dihydrofolate reductases.
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体外实验——
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体内实验——
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同义词6,6-Dimethyl-1-[3-(2,4,5-trichlorophenoxy)propoxy]-1,6-dihydro-1,3,5-triazine-2,4-diamine | WR99210 hydrochloride(47326-86-3 free base)
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通路Others
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靶点Other Targets
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受体pfDHFR
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研究领域——
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适应症——
化学信息
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CAS Number30711-93-4
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分子量431.14
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分子式C14H19Cl4N5O2
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纯度>98% (HPLC)
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溶解度——
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SMILESNC1=NC(N)=NC(C)(C)N1OCCCOC2=CC(Cl)=C(Cl)C=C2Cl.[H]Cl
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
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1-(3,4-dimethoxyphen...
1-(3,4-Dimethoxyphenyl)-2-(4-allly-2,6-dimethoxyphenoxy)propan-1-ol shows anti-staphylococcal activity against a total of five multidrug-resistant (MDR) and methicillin-resistant Staphylococcus aureus strains and the minimum inhibitory concentrations (MICs) are in the range of 128-256 ug/ml.
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DI-N-OCTYL PHTHALATE
邻苯二甲酸酯用作增塑剂和添加剂。用于毒理学研究以及邻苯二甲酸盐从食品接触材料 (FCM) 迁移到食品中而发生的食品污染风险评估研究。
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ATI-2341 TFA
ATI-2341 is an effective functionally selective allosteric agonist for the c-x-c chemokine receptor type 4 (CXCR4), which ACTS as a biased ligand in favor of G G G G G 1 activation instead of G G G G G 13.ATI-2341 activates the inhibitory heterotrimer G protein (Gi) to promote inhibition of cAMP production and induce calcium mobilization.ATI-2341 is an effective mobilization agent for myeloid polymorphonuclear neutrophils (PMNs) and hematopoietic stem and progenitor cells (HSPCs).
