Mitochondrial fusion promoter M1

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

线粒体融合启动子 M1 是一种线粒体动态调节剂。

Mitochondrial fusion promoter M1 is a mitochondrial dynamic modulator. Mitochondrial fusion promoter M1 preserves the mitochondrial function and promotes cellular respiration. Mitochondrial fusion promoter M1 alleviates cardiac and brain damage in rats with cardiac ischemia/reperfusion injury.

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Animal Model:Male Wistar rats (250-300g) receiving cardiac ischemia/reperfusion (I/R)Dosage:2 mg/kg Administration:I.v. 15 minutes before cardiac I/R injury Result:Increased brain mitochondrial fusion.Increased blood-brain barrier (BBB) tight junction protein, and reduced macrophage in?ltration in the brain.Reduced brain mitochondrial dysfunction and apoptosis, but it did not reduce mitochondrial oxidative stress.Reduced the expression of Alzheimer’s disease (AD)-related proteins.

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Others

Other Targets

Mitochondria

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219315-22-7

364.05

C14H10Cl4N2O

>98% (HPLC)

DMSO:46 mg/mL?(126.35 mM;?Need ultrasonic)

CC(c(cc(cc1)Cl)c1O)=NNc(c(Cl)cc(Cl)c1)c1Cl

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(-20℃)

With Ice Pack

≥ 2 years