TAK-981 ( Subasumstat )

产品货号. M23846 CAS No. 1858276-04-6

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

产品询价大包装询价加入购物车

产品名称

TAK-981
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

TAK-981是一种选择性SUMO化酶级联抑制剂，具有潜在的免疫激活和抗肿瘤活性。
产品描述

TAK-981 is a selective the SUMOylation enzymatic cascade inhibitor, has potential immune-activating and antineoplastic activities. (In Vitro):Subasumstat (TAK-981) is able to increase the production of type 1 IFN, thereby increasing type 1 IFN-mediated signaling, activating innate effector cells and enhancing the antitumor innate immune responses.(In Vivo):A single sub-cutaneous injection of Subasumstat (TAK-981) in naive Balb/c mice at the brachial lymph nodes induces activation of DCs.
体外实验

——
体内实验

——
同义词

Subasumstat
通路

Others
靶点

Other Targets
受体

SUMOylation
研究领域

——
适应症

——

CAS Number

1858276-04-6
分子量

578.1
分子式

C25H28ClN5O5S2
纯度

>98% (HPLC)
溶解度

DMSO:75 mg/mL (129.74 mM; Need ultrasonic)
SMILES

Cc1c([C@@H]2NCCc(cc3)c2cc3Cl)cc(C(c2c(N[C@H](C[C@@H]3COS(N)(=O)=O)C[C@@H]3O)ncnc2)=O)s1
化学全称

——