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UNC926 hydrochloride
CAS No. 1782573-49-2
UNC926 hydrochloride ( —— )
产品货号. M23797 CAS No. 1782573-49-2
UNC926 盐酸盐是一种甲基赖氨酸 (Kme) 读取结构域抑制剂。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥1663 | 有现货 |
|
| 10MG | ￥2461 | 有现货 |
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| 25MG | ￥3841 | 有现货 |
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| 50MG | ￥5199 | 有现货 |
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| 100MG | ￥6750 | 有现货 |
|
| 200MG | ￥8883 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
| 1 mL x 10 mM in DMSO | ￥1720 | 有现货 |
|
生物学信息
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产品名称UNC926 hydrochloride
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述UNC926 盐酸盐是一种甲基赖氨酸 (Kme) 读取结构域抑制剂。
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产品描述UNC926 hydrochloride is a?methyl-lysine (Kme) reader domain?inhibitor.
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体外实验UNC926 also exhibits a low micromolar affinity for the close homolog, L3MBTL3 ( IC50 of 3.2 μM), with a decrease in affinity for the other MBT domains and no binding to CBX7.UNC926 (1-25 μM) inhibits binding of the 3xMBT domain to H4K20me1.UNC926 inhibits the association of L3MBTL13xMBT with the appropriate histonepeptides in a dose-dependent manner. UNC926 does not have an effect on the binding of 53BP1 to H4K20me1, demonstrating specificity of UNC926 for L3MBTL1 over 53BP1.
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体内实验——
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同义词——
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通路Chromatin/Epigenetic
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靶点Epigenetic Reader Domain
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受体L3MBTL1|L3MBTL3|L3MBTL4
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研究领域——
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适应症——
化学信息
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CAS Number1782573-49-2
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分子量373.72
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分子式C16H22BrClN2O
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纯度>98% (HPLC)
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溶解度DMSO:150 mg/mL?(444.77 mM)
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SMILESO=C(C1=CC=CC(Br)=C1)N2CCC(N3CCCC3)CC2.[H]Cl
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Herold JM, et al. Structure-activity relationships of methyl-lysine reader antagonists. MedChemComm. 2012;3(45):45-51.
