5-Ph-IAA

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

5-Ph-IAA 是吲哚-3-乙酸 (IAA) 的衍生物，IAA 是一种植物激素，可作为癌症基因治疗的酶或前药组合。

5-Ph-IAA is a derivative of Indole-3-acetic acid (IAA), which is a plant hormone and acts as an enzyme or prodrug combination for cancer gene therapy.

Western Blot Analysis Cell Line:HCT116 cells Concentration:1 μM Incubation Time:6 hours Result:Depleted DHC1-mAC efficiently in HCT116 cells constitutively expressing OsTIR1(F74G).

Animal Model:Balb/c-nu female mice (7 weeks old; 16–20?g ) bearing mAID-BRD4 and TOP2A-mAC xenograft tumours cells Dosage:0 mg/kg, 1 mg/kg, 3 mg/kg and 10?mg/kg Administration:Intraperitoneally injection; every day; 7 days Result:Displayed significant tumour suppression of mAID-BRD4 xenografts and TOP2A-mAC xenografts.

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Others

Other Targets

Others

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168649-23-8

251.28

C16H13NO2

>98% (HPLC)

DMSO:125 mg/mL?(497.45 mM;?Need ultrasonic)

C1=CC=C(C=C1)C2=CC3=C(C=C2)NC=C3CC(=O)O

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(-20℃)

With Ice Pack

≥ 2 years